In 1907, New Jersey's state asylum at Trenton hired a Johns Hopkins–trained psychiatrist named Henry Cotton to clean up after a scandal. He threw out the straitjackets, retrained the staff and brought laboratory science into the asylum. Then he started pulling teeth, thousands of them, convinced that insanity was an infection hiding in the mouth.
A haven gone rotten
Dorothea Dix, the mental health reformer, founded the hospital in 1848. It was built on the Kirkbride Plan, a design by the Philadelphia psychiatrist Thomas Kirkbride, a Quaker who believed that sunlight, fresh air, privacy and dignity helped patients heal. By 1907 it had drifted a long way from that ideal. Dr. John Wesley Ward had run the place for three decades. He called his nearly 1,300 patients tainted creatures and spent his energy collecting seashells and art prints. Under oath, Ward admitted that the hospital had dumped typhoid-infected fecal matter into the Delaware River, which was the city's water supply. He also admitted that it had sold contaminated dairy products to the public and that attendants had beaten patients, possibly even killing someone.
Cotton looked like the cure. He had trained under Adolf Meyer, one of the most influential psychiatrists of the early 20th century, and had studied in Munich with Alois Alzheimer. After seeing Trenton, he wrote to Meyer: "Such a deplorable condition of affairs one could not believe could exist in an insane hospital today." Hundreds of patients had been restrained for years, and nobody even knew why. In his first two months, Cotton seized more than 700 pieces of restraint gear and boxed it up for the hospital museum. He retrained the attendants, started occupational programs and hired full-time social workers.
Madness in the mouth
Most psychiatrists thought madness was inherited, carried in the blood. Cotton didn't buy it. Researchers had just proven that paresis was the final stage of syphilis. Paresis was a paralytic disorder that also brought mania, grandiosity and sudden violence, and doctors diagnosed it in as many as one in five male asylum patients. If one germ could cause madness, Cotton figured, others were out there waiting to be found.
He found his answer in focal sepsis. The idea, championed by Dr. Frank Billings, a former president of the American Medical Association, was that a hidden infection in one spot, like the teeth, tonsils, sinuses or gallbladder, could poison the whole body. Billings called for ruthless removal. Cotton's first 50 patients to lose all their teeth showed disappointing results, so he started taking their tonsils too. In 1921, the hospital's dental department pulled 6,472 teeth, an average of 10 per admission. Cotton warned that bad teeth came from neglect, from dental work and from "promiscuous kissing." He declared that "modern dentistry is a serious menace to the whole country." In his view, crowns and root canals just hid the infection: "Unhealthy is the tooth that wears a crown."
Into the gut
When pulling teeth failed to work miracles, Cotton decided the infection must have already spread, and he followed it down into the gut. Vaccines made from patients' own bacteria also failed, so he teamed up with the abdominal surgeon Dr. J.W. Draper. By June 1919, they had performed 57 experimental surgeries, and seven patients had died. Their first case was Florence B. After her mother died, Florence became so anxious and depressed that she attempted suicide. Surgeons cut out part of her colon, and she lived one more week. Cotton concluded: "It served to confirm my opinion, however, that her trouble was largely in the intestinal tract."
In 1922, Cotton reported on 250 colon operations to the American Psychiatric Association: 25% of the patients recovered, 21% improved and 30% died. When patients or their families refused surgery, the surgeons operated anyway, and some patients fought as they were strapped onto gurneys. Cotton believed the work could succeed "only by being persistent, often against the wishes of the patient." He didn't hide any of it. He lectured, published and welcomed visitors from around the world. Wealthy people, who would never set foot in a state hospital, began paying Cotton for the same surgeries the state was handing out for free, and he built a thriving private practice on the side.
In full public view, a celebrated psychiatrist tried to cure insanity by pulling thousands of teeth and cutting out patients' colons, and hundreds of people died. The deaths didn't end his career. What forced him out was a complaint about his private practice.
The report that vanished
Not everyone was convinced. William White, who ran the federal mental hospital in Washington, objected to pulling every tooth from every patient. The textbook Diseases of the Nervous System mocked the trend as "an orgy of surgical intervention that has accomplished precisely nothing." In 1923, a study found no connection between hidden infections and mental illness.
Meyer sent another of his protégés, Dr. Phyllis Greenacre, to look into Trenton. She found sloppy records, hundreds of patients dead and thousands maimed. Many had lost every tooth and struggled to eat and speak. Even the patients Cotton counted as cured were often still clearly unwell. Meyer had privately felt troubled after his own visit, but he buried her report anyway.
In 1925, a New Jersey Senate committee led by William H. Bright began holding hearings. Edith Strong, a nurse who had been fired, testified that women were dragged to the operating table against their will. Cotton claimed she suffered from delusions, even though the hospital had fired her only after she began protesting. Prominent doctors praised his work on the stand, and Cotton walked away untouched.
Brought down by a side hustle
Money is what finally got him. The Mercer County Medical Society objected to a state employee double dipping, collecting a public salary while running a lucrative private practice on the side, and it pushed the state to act. In 1930, Cotton was named medical director emeritus, an honorary title that moved him out of the job. He lost the house, the car and the expense account, but he kept his salary, the equivalent of more than $155,000 today. A month later, President Hoover invited him to a White House conference on child health.
The abdominal surgeries at Trenton stopped when Cotton left. Other procedures continued until the end of the 1950s, and then the same operating room was put to use for the next miracle cure, the lobotomy. At his death, Cotton was praised as a man who practiced what he preached. He had pulled all his own teeth to treat his nervous breakdown, and he had pulled his wife's and both sons' teeth too. Then he announced that his angina had cleared up: "After the extraction of my last four lower teeth, my heart symptoms entirely disappeared." Not long after, he dropped dead of a massive heart attack at the Trenton Club.
